DOI: 10.36347/sjams.2021.v09i12.001

Pages: 1777-1781

Introduction: Acute Kidney Injury (AKI), formerly known as Acute Renal Failure, is characterized by a reversible increase in creatinine and nitrogenous waste product concentrations in the blood, as well as the kidney's failure to maintain proper fluid and electrolyte balance. Whether the etiology of AKI varies by area, the incidence of AKI in children appears to be increasing. The etiology of AKI in hospitalized children has shifted from primary renal disease to various causes during the last several decades, particularly in hospitalized children. As a result, further study is needed to determine the most recent trends in AKI in this region. Aim of the study: The aim of the study was to observe the etiology and its effect on outcome on children. Methods: This prospective longitudinal study was performed in the Department of Pediatrics, Dhaka Shishu Hospital, Dhaka, during the period of 12 months from January 2015 to December 2015. A total of 50 children were selected from the ones admitted into the hospital following the inclusion and exclusion criteria. A detailed history was taken, thorough physical examination and relevant laboratory investigations were done in all enrolled patients. All underwent necessary supportive care as needed until discharge or death. Result: In the present study, the mean age of the children was 2.8 ± 1.9 years, with the youngest one being 4 days and the oldest, 12.5 years. Male: female ratio was 1.8:1. Children in the age group of 1-5 years were most commonly affected. Pre-renal cause was the most common cause of acute kidney injury, present in 64% of the cases, and diarrheal complication was the most common disease in pre-renal cases. Mean serum creatinine were extremely high with Mean±SD levels of 4.03±2.81 (mg/dL). Conclusion: It was observed that, AKI was more common in early childhood (less than 5 years) than more than 5 years. Pre-renal causes etiology was the most common among the participants, and majority of the pre-renal.......