DOI: 10.36347/sasjm.2022.v08i02.003

Pages: 67-69

FVII (factor VII) is vitamin K-dependently synthesized in the liver. Hepatopathies, vitamin K deficiency, or use of vitamin K antagonists are the causes of acquired deficiency. Other types of acquired FVII deficiencies are rare. However, based on literature the incidence might be underestimated. The clinical manifestation of acquired FVII deficiency varies greatly in severity; asymptomatic course as well as severe life-threatening bleeding diathesis and fatal bleedings have been described. In this case report, we discuss a unique presentation of a 79-year-old male who was found to have cardiac tamponade revealing a severe acquired factor VII deficiency. A discordance between a prolonged PT and a normal aPTT was found in the biology lab report. And the diagnosis was confirmed by obtaining a factor VII activity assay. His management involved correction of his factor VII deficiency with fresh frozen plasma and pericardiocentesis.