DOI: 10.36347/sasjm.2016.v02i03.005

Pages: Page: 69-73

The aim of the study was to evaluate the effect of laser assisted hatching on clinical pregnancy rate of thawed embryos after vitrifaction. Inclusion criteria: Infertility patients who had frozen embryos for transfer, Age below 40, two or more frozen embryos available for transfer. Exclusion criteria: Blastocysts of the patients developed to hatching stage or hatched before vitrifaction. Patients with repeated implantation failure. Patients with uterine abnormalities or previous uterine surgery. The cases will be divided into two groups (A and B) each of them consisted of 60 patients. The patients will be divided into two groups. Group (A):60 patients Day 3 embryos or blastocysts will undergo laser assisted hatching using Saturn Vlaser device (RI). Half thickness of one quarter of the circumference of the zona. One hour after thawing of the embryos and two hours before embryos transfer. Group (B):60 patients will undergo frozen - thawed embryos transfers without laser assisted hatching. Endometrial Preparation and embryos Transfers the endometrium will be prepared by administration of oral E2 and vaginal Micronized Progesterone. Age ranged between 22.0-36.0 and 23.0- 37.0 years with the mean of 28.94.68 and 27.85.68 years for group A and group B respectively, with no statistical significant differences. Normal weight were found in 68.33% and 80%, over weight were found in 20.0% and 13.33% and obese were found in 11.67 and 6.67% for group A and group B respectively, there were no statistical significant differences between the two studied groups regarding weight.