DOI: 10.36347/sjams.2022.v10i02.004

Pages: 176-180

Background: Diabetes mellitus (DM) is a complex and heterogeneous chronic metabolic disease caused by elevated levels of blood glucose. Although myocardial ischemia is known to be significantly related to the development of coronary collateral vessels (CCVs), there is considerable variation between patients with ischemic heart disease in the presence of collateral development. Methods: This observational study was done in Department of Cardiology, Mymensingh Medical College Hospital, Bangladesh from January to December 2020. Out of 110 patients who had a stenosis of >95% in any major coronary artery in angiograms were included in the study. Of these patients, 35 patients constitute the diabetic group. Remaining 75 patients were non-diabetic. For case-control matching, 35 non-diabetic patients were selected randomly and were included in the control group. The CCVs were graded according to the Rentrop scoring system, and the collateral score was calculated by summing the Rentrop numbers of every patient. Results: There was no statistical difference between patients with and without DM in clinical baseline characteristics. The mean number of diseased vessels in the DM group (2.11±0.75) was higher than that in the nondiabetic group (1.64± 0.73 P.016). The mean collateral score was (1.12± 0.85) in the DM group and (1.96± 1.62) in the control group. After confounding variables were controlled for, the collateral score in the diabetic group was significantly different from that in the nondiabetic group (p=0.015). Conclusion: Thus, we can speculate that DM is an important factor affecting CCV development. Increased risk for diabetic patients after acute coronary syndrome presents a real therapeutic challenge and must be multidisciplinary, involving the cardiologist, the diabetologist and the general practitioner, who is a constant pillar in this equation. In findings suggest that CCV development is poorer in patients with DM and without DM patients. Thus, we can ...........