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Scholars Journal of Applied Medical Sciences | Volume-10 | Issue-02
Coagulopathy and COVID-19: About 102 cases
Boukoub Naila, Errifaiy Hayate, Nissrine Tajellijiti, Youssef El Ouardi, Mohammed KHallouki
Published: Feb. 11, 2022 | 142 85
DOI: 10.36347/sjams.2022.v10i02.010
Pages: 206-210
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Abstract
Introduction: The SARS-COV 2 virus, in particular in its severe form, appears to be associated with a large number of thromboembolic events, an incidence all the higher as the patients are admitted to intensive care units or intensive care units. The objective of our work is to identify the prognostic factors for the occurrence of thromboembolic complications of covid 19 in intensive care. Material and method: It is a single-center retrospective study, carried out in the intensive care unit of the IBN TOFAIL hospital in Marrakech. We included all covid 19 patients hospitalized from November 15, 2020 to January 10, 2021 confirmed by RT-PCR or by compatible CT lesions. The qualitative variables were expressed in% and compared by Chi-square test or Fisher's test. The quantitative variables were expressed as a mean (± standard deviation) or as a median (Percentile), and compared by Student's or Mann-Whitney t-test. For multivariate analysis, we used multiple logistic regressions using SPSS version 19 for Windows. A p <0.05 is considered significant. Results: We collected 102 patients hospitalized with SARS-COV 2 pneumonia during the study period. The mean age was 61.81 ± 11 with a predominance of men (65.7%), 45.4% of the patients had a BMI between 30-34.9 Kg / m². Diabetes predominates in 59.8% followed by hypertension in 40.2%, heart disease, dysthyroidism and renal failure were observed in 8.8%, 3.9% and 3.2% of cases, respectively. Forty-two percent of patients presented with coagulopathy on admission, defined by D-Dimer levels> 0.5µg / ml, fibrinogen> 4g / l and thrombocytopenia. The occurrence of an arterial or venous thromboembolic event was found in 24.5% of cases with mainly venous manifestations, i.e. thirteen pulmonary embolisms, three catheter thromboses and two deep vein thromboses and five arterial accidents represented by three ischemic strokes, two limb ischemia and one myocardial infarction. The presence of this coagulopathy associated with ............