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Scholars Journal of Applied Medical Sciences | Volume-10 | Issue-02
“Study of Status of Sympathovagal Balance in Offsprings with Family History of Hypertension and in Those without It”
Dr. Dalia Biswas, Dr. Prerna Agarwal
Published: Feb. 22, 2022 | 134 90
DOI: 10.36347/sjams.2022.v10i02.020
Pages: 253-257
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Abstract
Background: Autonomic functions, sympathetic and vagal/ parasympathetic, are found to be deranged in hypertensive subjects. The derangement of autonomic functions in terms of sympatho-vagal imbalance has also been found in off-springs of hypertensive people. Method: Spectral analysis of heart rate variability (HRV) was recorded in 30 subjects of control group & 30 subjects of case /study group( offsprings of hypertensive parents) before and after Hand Grip Test(HGT). Body mass index (BMI), basal heart rate (BHR), blood pressure (BP) was recorded at the outset. Spectral indices of HRV included Standard deviation of NN intervals (SDNN), total power (TP), normalized low frequency power (LFnu), normalized high frequency power (HFnu), ratio of low frequency power to high frequency power (LF-HF ratio), mean heart rate (mean RR), square root of the mean squared differences of successive normal to normal intervals (RMSSD) and the number of interval differences of successive NN intervals greater than 50 ms (NN50). Result: In study group SDNN & LF/HF finding was significant which means there is a sympathetic dominant effect. Pre and Posttest HGT and HRV values were found to be significant when study and control groups were compared. This means changes occur in sympathetic variables before actual onset of hypertension. No correlation was seen as regards to HRV & BMI. Conclusion: It can be concluded that offsprings of Hypertensive parents tend to have some degree of autonomic imbalance before the actual onset of essential hypertension.