DOI: 10.36347/sasjm.2022.v08i03.015

Pages: 188-192

Introduction: Acute coronary syndromes without ST segment elevation are heterogeneous entities. Troponins contribute to the early identification of patients at high risk for cardiac complications. The objective of this work is to study the severity of coronary artery disease according to the ultrasensitive troponin T (T us) level. Methods: We have performed a descriptive retrospective of patients hospitalized in the cardiology department of CHU Mohammed VI in Marrakech, between January 2018 and February 2022 for acute coronary syndromes without ST segment elevation. Patients were divided into two groups according to the rate of troponin Tus. Results: 50 patients were included, comprising 35 men and 15 women. Group 1, made of 20 patients whose ultrasensitive troponin T level is less than 4 times normal, group 2, whose troponin T level is more than 4 times normal, made of 30 patients. Demographic analysis shows that there is no significant difference between the two groups in terms of average age and sex. Hypertension is slightly more common in Group 1 (45% vs. 43.3%). De novo angor was more frequent in group 1 compared to group 2 (10% vs 6.7%;p=0.01). At electrocardiogram, subendocardial lesions are more in Group 2 (15% vs. 43.3%; p=0.0006). Group 1 had angiographical coronaries more frequently normal or non-significant coronary involvement compared to group 2 (40% vs 6.67%; p<0.001). Tritroncular lesions are more frequently found in Group 2 (33.3% vs. 5%;p=0.02). Monotroncular and bi-roncular lesions are recorded identically in both groups. Ischemic recurrences are more common in Group 2 (35% vs. 46.6%;p=0.02). Conclusion: Stable Troponin US levels are associated with the degree of coronary involvement, and frailty measurements were significantly associated with the severity of coronary lesions, this could help to identify patients who are at a high risk of death. These findings may help clinicians guide further diagnostic assessment.