DOI: 10.36347/sasjs.2022.v08i03.012

Pages: 126-133

Background: Mastalgia and fibroadenomas are common among the women in reproductive age group. Thyroid dysfunction has been implicated as the etiology. Objective: To identify the relationship of Hypothyroidism in the causation of developing Mastalgia. Methods: This case-control study was carried out in the Department of General Surgery, BSMMU, Dhaka, between January 2019 to June 2019. A total of 90 patients with mastalgia due to nonadherence to antithyroid therapy, out of which 60 patients with Hypothyroidism were considered as a group I and 30 without Hypothyroidism were considered as group II. For statistical analyses of the results generation, using window-based computer software devised with Statistical Packages for Social Sciences (SPSS-23). Results: The majority 96.7% of patients were married in group I and 85.0% in group II. Nearly three fourth 73.3% of patients had not a history of oral contraceptives in group I and 15.0% in group II. The mean TSH was 9.23±8.84 mlu/l in group I and 3.25±1.15 mlu/l in group II. The mean FT3 was 1.96±0.68 (pg/ml) in group I and 3.10±1.1(pg/ml) in group II. More than half 53.3% of patients had mastalgia occurring within a year in group I. Mastalgia only found 55.3% and 30.0% in group I and group II respectively. More than half 52.2% of patients had taken fatty food, fast food, red meat daily in group I and 15.0% in group II. Physical exercise performed frequently found 8.3% and 50.0% in group I and group II respectively. The difference was statistically significant (p<0.05) between the two groups. Conclusion: No history of oral contraceptive, consumption of fatty food, fast food, red meat, and never engagement in physical exercise were significantly more common in mastalgia patients with hypothyroidism. There was an association of thyroid dysfunction in patients with mastalgia.