DOI: 10.36347/sasjm.2022.v08i04.008

Pages: 282-284

Mitral valve prolapse, an abnormal displacement into the left atrium of a thickened and redundant mitral valve during systole, is a relatively frequent abnormality in humans and may be associated with serious complications. One of the possible consequences of this condition is that the malfunctioning mitral valve allows backflow of blood in the left atrium, which, when severe, leads to left ventricular enlargement and failure. Besides severe mitral regurgitation, mitral valve prolapse has been associated with serious complications such as bacterial endocarditis and sudden death. Marfan syndrome is an autosomal dominant systemic disorder of the connective tissue. Patients affected by the Marfan syndrome carry a mutation in one of their two copies of the gene that encodes the connective tissue protein fibrillin-1. Marfan syndrome affects most organs and tissues, especially the skeleton, lungs, eyes, heart, and the large blood vessel that distributes blood from the heart to the rest of the body. We report a case of Marfan syndrome in a 30 years old patient presenting with mitral valve prolapse, tricuspid regurgitation associated with severe ocular, musculoskeletal abnormalities.