DOI: 10.36347/sjams.2022.v10i04.022

Pages: 567-570

Introduction: Anxiety is considered as a major complaint in majority of the patients who are supposed to consult with surgeons for a possible surgical procedure and also as an effective and preventing factor in patients’ resistance to surgical procedures. Preoperative anxiety and its associated problems such as severe changes in hemodynamic parameters, the occurrence of arrhythmia with occasional dangerous hemodynamic complications are more common during anesthesia. Objective: To assess the effects of low dose propranolol to haemodynamic Changes produced by Stress during Surgery. Materials and Methods: A prospective observation study was carried out at the Dept. of Anesthesia, 250 Bedded General Hospital, Noakhali, Bangladesh from January to December 2021. Ninety (90) patients of ASA physical status admitted in hospitals for abdominal diseases had undergone operation of an average duration of 30 to 60 minutes under general anesthesia were selected for the study. Both male and female patients within age group 18-65 years were included. The anaesthetic procedures were explained and reassured to each patient after arrival of patient in operation theatre. Intravenous access was secured. Results: In our study both groups were homogenous as regard to age, weight, height and ASA physical status. The duration of surgery was also statistically matched with each other. The effects of placebo and propranolol on heart rate, systolic arterial pressure and rate pressure product immediately after intubations and during pre-operative period showed significant differences than that of base line values.It was shown the baseline values of heart rate of the two groups were similar. Base line systolic arterial pressures (SAP) were also similar. But it was significantly different within groups. Heart rate was significantly higher in placebo group (Group A) immediately after intubation and at 5, 15, 30, 60 minutes of per-operative period compared to the propranolol group (Group B). .....