DOI: 10.36347/sjams.2022.v10i04.027

Pages: 592-597

Background: Cardiovascular diseases caused an estimated 17.3 million deaths in a year. Around 40% of these cardiovascular deaths are due to coronary heart disease. It is projected that coronary heart diseases will remain a leading cause of morbidity and mortality for many years to come. Atherosclerosis, the main underlying pathologic process for coronary heart diseases, is a chronic disease state of the coronary arteries that slowly develops over decades before becoming clinically significant. Its pathophysiology is complex, including inflammatory and immunological events which are considered to be of central importance in the initiation and progression of atherosclerotic plaques. Gradual chronic progression of coronary atherosclerosis may result in luminal narrowing causing symptoms of angina. Aim: To study neutrophils to lymphocyte as inflammatory markers in long standing (chronic) coronary artery disease. Material and methods: A Cross sectional Observational study was conducted at outpatient department of Medicine in Krishna Hospital and research centre. For a period October 2019- October 2021. Registration of patients was from October 2019. Such 72 cases were studied. They were registered when admitted under Medicine department. At the time of registration, the patients with exclusion criteria were not enrolled for study. The main objective of this study was to study clinical and laboratory parameters of patients with coronary artery disease, to do Coronary angiographic evaluation of cardiac functions. Results: Mean Age in Years Was 56.72+5.5. Majority 77.77% were in age group of 50 to 60 years and 70.83% were males. Patients mainly complained of chest pain 97.22%, followed by breathlessness 86.11%, palpitation 15.27%, retrosternal burning 13.88%, sweating 15.27%, tightness in chest 13.88% and tremors 13.88%. Conclusion: Study concluded that there is a strong association between NLR and severity of coronary artery disease. Among Cases having positive ..........