DOI: 10.36347/sjams.2022.v10i04.033

Pages: 630-634

Factor V Leiden mutation is an inherited disorder of coagulation. Factor V Leiden resists the effects of activated protein C, so it takes longer to turn off Factor V Leiden. As a result, clotting goes on longer than usual. It’s associated with thrombotic events that classically involve the venous thrombosis and rarely arteries. However, the role of factor V Leiden in the genesis of arterial thrombosis is not yet fully understood. We report a case of a young woman with multiple thromboembolic events including pulmonary embolism, renal associated to hepatic infarction, apical thrombus on the left ventricle and ischemic stroke, in the context of a factor V mutation.