DOI: 10.36347/sjams.2022.v10i05.015

Pages: 772-775

Background: Cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury that leads to portal hypertension and end stage liver disease. The exact prevalence of cirrhosis worldwide is unknown. Cirrhosis prevalence was estimated at 0.15% or 400,000 in the USA where it accounted for more than 25,000 deaths and 373,000 hospital discharges in 1998. This may be an underestimation as we recognize the high prevalence of undiagnosed cirrhosis in both NASH and hepatitis C. Similar numbers have been reported from Europe, and numbers are even higher in most Asian and African countries where chronic viral hepatitis B or C are frequent. Since compensated cirrhosis often goes undetected for prolonged periods of time, a reasonable estimate is that up to 1% of populations may have histological cirrhosis. Aim: To study clinical profile of cirrhotic patients. Material and Methods: A cross-sectional observational study was carried out at Inpatient Department of Medicine of tertiary care hospital. Total 100 cases were studied. Registration of patients was from October, 2019 to March 2021. They were registered when admitted under Medicine department. At the time of registration, the patients with exclusion criteria were not enrolled for study. The main objective of this study is to study the biochemical and bacteriological profile of cirrhotic patients. At the time of registration, the baseline information was taken especially with respect to sociodemographic factors, clinical findings, and other investigations. The data thus collected was analysed to study clinical profile of cirrhotic patients. Results: Mean age in years was 55.1 +15.06, ranging from 24 to 75. Majority 40% were in age group of 40 to 60 years. Majority 68% were males and 32% were females. Mean SBP was 150.15+21.54 ranging from 100 to 210. 66% had increased SBP i.e.>140 mm of Hg and Mean DBP was 91.64+11.87, ranging from 60 to112. ...........