DOI: 10.36347/SASJS.2019.v05i09.005

Pages: 355-359

Gastrointestinal Stromal Tumors "GIST" are a very rare form of digestive tract cancers belonging to the family of sarcomas. The aim of this study is to establish the epidemiological and evolutionary profile as well as the diagnostic and therapeutic difficulties of this malignant pathology managed in a developing country. A retrospective study spread over 13 years from January 2006 to December 2018, was conducted at the Visceral Surgery Service of university hospital Mohammed VI in Marrakech (Morocco) have collated 64 cases of gastrointestinal stromal tumors. The average age of our patients was 53 years. The average progression time was 7.5 months. The Biopsy confirmed the diagnosis in 17 cases and surgery in 47 cases. The main histological form was fusiform (60.94%). GIST in our series had an average tumor size of 8.2 cm with a positive C-Kit in all cases. The risk of progression was identified in 56 cases, 10 of which were high risk. Surgery was the main treatment for patients in our study. After a mean fellow of 31 months, 43 of the evaluable patients in our series are in full remission maintained, 10 cases have local and/or metastatic recurrence and one death. Although the recommendations are published for the treatment of these tumors, these still raise many problems both diagnostic and therapeutic in our context.