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Scholars Journal of Applied Medical Sciences | Volume-10 | Issue-05
Viral Hepatitis B and Chemotherapy
I. Elkoti, R. Laroussi, R. Berreda, A. Benhamdane, O. Mohammed, T. Addajou, S. Mrabti, S. Sentissi, F. Rouibaa, A. Benkirane, H. Seddik
Published: May 18, 2022 | 163 127
DOI: 10.36347/sjams.2022.v10i05.019
Pages: 790-792
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Abstract
Patients with chronic hepatitis B treated with chemotherapy or immunotherapy are at risk of viral reactivation, which can have serious or even fatal consequences [1]. Patients treated with chemotherapy for haematological disease have a known risk of hepatitis B virus (HBV) reactivation with an estimated incidence of 14-72% [2]. The majority of chemotherapy drugs can induce HBV reactivation in patients with HBs-positive antigen [3]. HBs testing should therefore be recommended prior to chemotherapy. Preventive antiviral treatment will reduce the risk of HBV reactivation.