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Scholars Journal of Applied Medical Sciences | Volume-10 | Issue-05
Breast Arterial Calcification on Mammography and Risk of Coronary Artery Disease
Happy, S M Ear -E-Mahabub, Nazir Uddin Mollah, Md. Emran Hossain, Dr. Halima Khatun, Md. Magfur Rahman
Published: May 24, 2022 | 148 78
DOI: 10.36347/sjams.2022.v10i05.023
Pages: 810-815
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Abstract
Background: Breast arterial calcification (BAC) is generally detected on screening mammography which shows medial calcification of the mammary arteries. On the other hand, CAD is an important cause of morbidity and mortality worldwide. BAC is associated with risk factors for cardiovascular disease specially in patients who underwent screening mammography. Methods: This study was a cross-sectional observational study that was conducted at Bangabandhu Sheik Mujib Medical University. Dhaka. Bangladesh during the period of January 2018- December 2022. The sample size for this study was 70. Result: The mean ±SD age of the respondents who underwent mammography was 58± 8 years where who had breast arterial calcification it was 62±7 years. Total cholesterol was 5.1±1.9 and 5.2±2.0, ASSIGN score was in 15±10.8 and 18.1±11.0, coronary artery calcium score was in 0(0,52) and 13 (0, 107), any coronary artery disease on CCTA was in 35(50%) and 7(58.3%), obstructive coronary artery disease on CCTA was in 10(14.3%) and 2(16.7%) cases. Coronary artery calcification 5 was found in TP, 14 was in TN, 3 was in FP, 14 was in FN, 2 was in sensitivity, 7 was in specificity, 6 was in PPV, 5 was in NPV and .545 was in AUC and followed by coronary artery calcification (>400 AU) was in 1, 27, 8, 1, 3, 6, 1, 9 and 0.554, any coronary artery disease on CCTA was in 5, 14, 3, 14, 2, 7, 6, 5 and 0.546, obstructive coronary artery disease on CCTA was in 2, 25, 7, 4, 3, 7, 2, 8 and 0.556. Conclusion: BAC on mammography is a potential woman-specific risk predictor for CAD and is also related to the growth of coronary atherosclerosis proven by CCTA having important clinical implications. BAC is also strongly associated with the development of CAC and CAP.