DOI: 10.36347/sjmcr.2022.v10i05.019

Pages: 485-488

Fernand Widal syndrome is a condition with an often severe triad of asthma, intolerance to acetylsalicylic acid and nasosinus polyposis. Aim of the work: to determine the clinical peculiarities of the patients carrying this syndrome in our context.Patients and methods: we carried out a retrospective study carried out over a period of five years at the service of respiratory diseases of the University Hospital of Casablanca, collecting 16 cases of patients carrying this triad. Result: The average age was 44.2 years, with a female predominance (75% of cases). All patients had atopy, mainly rhinitis and conjunctivitis. In 62.5% of the cases, asthma was moderate to severe with moderate to severe obstructive airways in 60% of cases. Five patients had a history of hospitalization for severe exacerbation of asthma in one medical facility and four others in intensive care unit with intubation in three patients. All patients were on inhaled corticosteroids and long-acting bronchodilators using antileukotrienes. Despite optimal medical treatment and polyp surgery in patients with locally resistant rhinitis, 38% of rhinitis cases and 56.6% of severe asthma cases were poorly controlled. In conclusion, patients with SFW have difficult-to-control asthma and rhinitis under optimal medical treatment, sometimes requiring desensitization with aspirin and the emergence of new therapies.