DOI: 10.36347/sjams.2022.v10i06.024

Pages: 1016-1020

Background: Leukemia is the most common malignancy at the age of under 15 years. Main subtypes of leukemia found in children are Acute Lymphoblastic Leukemia (ALL), with a percentage of 80%. Acute lymphoblastic leukemia (ALL) is one of the most common malignancies of childhood. Aim of the study: The aim of this study was to investigate the immunophenotyping profiles of childhood acute leukemia in Dhaka Medical College Hospital, Dhaka. Methods: This Cross-sectional study was conducted in the department of paediatrics in Dhaka Medical College Hospital, Dhaka, Bangladesh. A total 80 patients were selected as the study subjects. Immunophenotyping allowed classification into acute myeloid leukemia (AML) and ALL (B-lineage and T-lineage ALL). Result: Among of 80 samples, where we found maximum 51(63.75%) were Male and 29(36.25%) were Female. In age distribution, where maximum 38(47.5%) were (0-5) years of age, 32(40%) were (6-11) years of age, 10(12.5%) were (12-15) years of age, respectively. We have found, 57(71.25%) were B lineage ALL, then 10(12.50%) were AML, 9(11.25%) were T Cell ALL, 2(2.50%) was CML, 1(1.25%) was Mixed, 1(1.25%) was Aplastic. Conclusion: Immunophenotyping in a cross-sectional study proved feasible and appears particularly important for prognostic assessment of childhood leukemia in low-income countries such as Bangladesh.