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Scholars Journal of Applied Medical Sciences | Volume-10 | Issue-06
A Comparative Study between AFB Smear Microscopy (Ziehl-Nelsen) and Gene-Expert Technique in the Diagnosis of Tuberculosis
Ajobiewe JO, Akogwu NG, Akhigbe AU, Ale SA, Adigun KA, ErukubamiJI, Ajobiewe HF, Yashim AN, Alau KK, Salami AO, Udefuna PA, Ogundeji AA, Umeji LC, Okoye WM, Aniakor GC, Ogakwu MN
Published: June 30, 2022 |
129
90
DOI: 10.36347/sjams.2022.v10i06.025
Pages: 1021-1025
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Abstract
611 samples were collected and tested for AFB using the Zeihl-Neelsen technique. Of the 611 samples tested, 525 were negative with Ziehl-Neelsen AFB smear microscopy. The 525 negative samples were tested using the genexpert technique. 53 out of the 525 samples were positive with genexpert with a percentage positivity rate of 10.1%. The data analysis was done using the student’s t-test. There was a significant difference between the sensitivity of Ziehl-neelsen technique when compared with genexpert technique (t= 3.32; p< 0.05). Hence, there was a demonstrated increase in laboratory based TB detection using Xpert MTB/Rif compared to smear microscopy (ziehl-neelsen).