DOI: 10.36347/SASJS.2019.v05i11.003

Pages: 419-422

Background: In acute inflammatory conditions such as acute appendicitis there is dysfunction of kupffer cells and hepatocytes due to bacterial overload which reach the liver via portal circulation causing increase in the serum bilirubin levels. Acute inflammatory cytokines can also lead to raised serum bilirubin levels without much rise in the serum liver enzymes levels. Aim: To correlate hyperbilirubinemia with acute appendicitis and its complications such as appendicular perforation and gangrenous appendicitis. Material and Methods: This is a prospective study conducted at department of general surgery KIMS, Hubli during the period of august 2017 to august 2018. 50 cases of acute appendicitis were selected. All the basics investigations were done such as complete blood count, LFT and ultrasound. Liver function test was done preoperatively. Cases underwent open appendicectomy and intraoperative findings were noted. Clinical examination, laboratory values and operative details were compiled and analysed and following observations were made. Results: Out of 50 cases 38 had raised serum bilirubin. No associate raise in the liver enzymes. Conclusion: This study comes to the conclusion that there is correlation between acute appendicitis (and its complications) with the raised serum bilirubin. There is raise in both the direct and indirect bilirubin. There is no raise in the liver enzymes