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Scholars Journal of Applied Medical Sciences | Volume-1 | Issue-01
Study of anxiolytic activity of some essential oils used by inhalational exposure in mice
Habibur Rahman, M. Chinna Eswaraiah, Saarangi Ramesh, B.Maruthi Rao
Published: Feb. 28, 2013 | 118 78
DOI: 10.36347/sjams.2013.v01i01.001
Pages: 1-4
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Abstract
Abstract – At present competitive life due to stress and strain in work like enhancing burden in learning, pressure of doing well, worry about settlement or jobs are one of the major cause of human anxiety and affects one-eighth population worldwide. Aromatherapy is getting popularity as alternative therapy for treatment and management of CNS disorders. This present study was taken to study the affect of Sandalwood Oil, Eucalyptus Oil, Lemon Oil, Jasmine Oil, and agarwood on Behavioral anxiolytic animal models by exposing as inhalational route. Anxiolytic activity was studied in mice using Hole Board Test and Elevated Plus Maze after exposure of essential oils in inhalational chamber for 15 min. The no. of head dipping and line crossing in Hole board test and no. of entries and time spent in open arms are taken as index for measuring anxiolytic activity. From this behavioral study it can be concluded that by inhalational exposure of sandalwood oil, jasmine oil and agarwood oil produces anxiolytic activity but Eucalyptus oil and lemon oil may be anxiogenic. Although as observed, eucalyptus oil significantly decreased mobility in animals and that may be reason of opposite result in these behavioural studies. By further research, we can frame the pharmacological basis of aromatic oil for the treatment oil CNS diseases.