DOI: 10.36347/sjams.2013.v01i01.003

Pages: 9-12

Abstract – The present study was carried to evaluate the hepato-protective activity of ethanolic extract of Aquilaria agallocha leaves (EEAA) against CCl4 induced hepatic damage in rat. The hepatoprotective activity was evaluated by estimated serum hepatic enzyme levels and hisopathological study of liver tissues of rats. Ethanolic extract of Aquilaria agallocha leaves (EEAA) at dose 200 mg/kg and 400mg/kg body weight were administered orally for 10 days in rats and compared with standard silymarin (100 mg/kg) orally. The results showed significant decrease in serum ALT, AST and ALP levels treated groups which were increased due to CCl4 induced liver damage are comparable with standard drug. Histopathological study of liver tissue ravels the hepatoprotective activity of EEAA