DOI: 10.36347/sjmcr.2022.v10i07.018

Pages: 676-679

Introduction: Primary angiosarcoma of the breast is exceedingly rare, and represents around 0.04% of malignant breast neoplasm. Radiographically, breast angiosarcomas exhibit no pathognomonic features. They often appear as ill-defined masses on mammograms. The diagnosis is essentially based on the histological assessment of the excised sample. The treatment is based on simple mastectomy. This neoplasm carries a very poor prognosis, with a five- year survival of 8–50%. Case Report: We report a case of a 20- year-old woman with a highly vascular mass in her left breast which is suggestive of malignancy at radiology. The patient underwent a mastectomy. The histology of tumour showed dilated vascular spaces lined by atpical endothelial cells infiltratimg throughout the breast parenchyma. There are solid areas comprising highly atypical spindle or epitheloid cells with hyperchromatic round, oval or spindle nuclei with marked anisonucleosis. On immunohistochemistry the tumour was found positive for CD31, the diagnosis of Angiosarcoma Grade III was made. The patient is now receiving chemotherapy as known on two-month follow-up of the patient. Conclusion: Young women with solid-appearing breast tumors that are highly vascular at the time of biopsy should be considered malignant until proven otherwise.