DOI: 10.36347/sjams.2013.v01i05.0010

Pages: 395-399

Antimicrobial resistance is not only increasing the healthcare costs, but also the severity and death rates from certain infections that could have been avoided by prudent and rational use of the existing and newer antimicrobial agents. Prudent and rational use of antimicrobial is possible by forming local, national and global wide Antibiogram. Urinary tract Infection (UTI) is among the most common infections described in outpatient department and hospitals inpatients. Klebsiella pneumoniae (K. pneumoniae) accounts for 2nd highest organism isolated from urine samples of UTI patients after Escherichia coli. The present study is undertaken to determine the antimicrobial susceptibility pattern of K.pneumoniae isolated from urine samples of UTI patients of Peoples College of Medical Science & Research Centre and hospital. Between January 2010 and December 2011, a total of 1450 urine specimens processed in the laboratory, of which 65 (15.4%) yielded K. pneumoniae. Organisms were identified by conventional methods. Antimicrobial susceptibility testing was done by the disk diffusion methods. K.pneumoniae is showing good antimicrobial susceptibility for imipenem, gatifloxacin, amikacin, gentamicin, ampicillin/Sulbactam, levofloxacin and amoxicillin/clavulinic acid. An attempt has been made in this study to recognize the K.pneumoniaein patients of UTI of tertiary care hospital, Bhopal M.P.; to record the antibiogram and probable drug of choice for K.pneumoniae considering the antibiotic susceptibility testing, cost, side effects and many other factors.