DOI: 10.36347/sjams.2013.v01i05.0061

Pages: 595-599

The present study was to determine the degree of fall in hemoglobin , hematocrit and need for blood transfusion following delivery in those receiving intramuscular methylergometrine and intramuscular oxytocin and also to compare the safety and efficacy of those two drugs. This was a randomized, comparative, prospective, single blinded, interventional,Hospital based clinical trial conducted in the labour room and maternity ward at R.G.Kar Medical College and Hospital, Kolkata. , recruiting 400 women after matching, 200 in each two groups- Group A receiving intravmuscularmethylergometrine, Group B receiving intramuscular oxytocin. 3rd stage blood loss, systolic blood pressure, diastolic blood pressure, hemoglobin and hematocrit value before and after giving uterotonic are measured and recorded..Side effect of both uterotonic were recorded. Data were analysed by using SPSS Software version 18. The mean duration of the 3rd stage was 6.40 minute in ergometrine group compared to 7.31 minute in oxytocin group. The difference was not statistically significant. The average blood loss was 194.7 ml in ergometrine group compared to 188.9 ml in oxytocin group. The fall in hemoglobin percentage was 0.89 g/dl in ergometrine group compared to 1.118 g/dl in oxytocin group. The difference in observation of both groups was statistically not significant (p>0.05). The fall in hematocrit was 2.41 ergometrine group compared to 2.65 in oxytocin group. The difference in observation of both groups was statistically not signifanat (p>0.05). The incidence of post partum hemorrhage was 3% in both the groups. There were 1 case of retained placentain either of the groups. Need for additional oxytocics was 4% in both the groups as they were given only when the blood loss is more than 500 ml in the present study. There was increase in blood pressure in ergometrine group and slight decrease in blood pressure in oxytocin group. Vomiting, leg cramp and chest pain were associated with inj meth