DOI: 10.36347/sjams.2013.v01i06.0061

Pages: 924-927

Gastro Esophageal Reflux Disease (GERD) is a complex disorder caused by the reflux of gastric contents into the esophagus either with or without complications. The objective of present study is to determine the correlation between clinical, endoscopic and histological findings in patients of GERD. This prospective study has been done in the Department of Medicine, Sri Aurobindo Medical College and P.G. Institute, Indore (MP). 100 patients of GERD has been taken for study during the year 2012-2013.The patients who fulfilled the clinical criteria of GERD along with inclusion & exclusion criteria has been studied. Endoscopy and histopathology examination were done in all patients. Descriptive statistical analysis and evaluation were done to analyze the result. Chi-square test was applied and ‘P’ value was determined accordingly In our study all the cases have presenting complaint of epigastric pain, after endoscopy of these patients more than 50% of cases shown esophagitis out of which 28% cases had only esophagitis and 24% cases had hiatus along with esophagitis, 14% cases had only hiatus hernia, Barrett’s esophagus was present endoscopically in 8 cases and 26 cases had normal endoscopy. We conclude that severity of clinical symptoms does correlate with endoscopic findings while histopathological findings correlate with those of endoscopic findings but not with clinical symptoms.