DOI: 10.36347/sjams.2013.v01i06.0064

Pages: 937-942

This study was carried out to investigate the anti-inflammatory activity of the methanolic extract of Trigonella foenum grecum seeds in carrageenan saline induced paw edema in rats, The methanolic extract of Trigonella foenum grecum showed significant anti-inflammatory efficacies against carrageenan induced paw edema. Rats that were ingested with 1000mg of extract/kg, showed a significant decrease in edema size in the second, fourth and twenty fourth hours and inhibition percentage at 13.49, 41.17, 41.17, 38.46 and 33.33 at the first, second, fourth, sixth and twenty fourth hours respectively. Hematological values of PCV, RBC and Hb showed no significant difference. Trigonella foenum grecum extract possesses an anti inflammatory activity. The extracts of this plant are safe at high doses.