DOI: 10.36347/sasjs.2022.v08i07.004

Pages: 487-490

Adenomyomatosis (ADM) of the gallbladder (GB) is a benign disease, defined by an enlargement of the mucosal epithelium which invaginates into the interstices of a thickened muscle forming so-called Rokitansky-Aschoff sinuses. Three forms exist: segmental, fundic and more rarely diffuse. The etiopathogenesis is not yet elucidated, but chronic inflammation of the gallbladder wall seems to be involved. Prevalence of ADM in cholecystectomy specimens is estimated between 1% and 9% with a balanced sex ratio. ADM gallbladder is usually asymptomatic, however it can manifest as hepatic colic, even in the absence of associated gallstones. The preoperative diagnosis is mainly based on ultrasound (US) which identifies intra-parietal pseudo-cystic images and "comet tail" artifacts. MRI with MRI cholangiography sequences is the reference examination with characteristic "string of pearls" images. If the clinical picture is symptomatic or in case of tumor suspicion, cholecystectomy is then justified the discovery of ADM on a cholecystectomy specimen does not require special monitoring.