DOI: 10.36347/sjams.2022.v10i08.002

Pages: 1176-1180

Aim: To observe the association between dyslipidemia and CSME in Type – II diabetes mellitus. Method: With convenience type of sampling technique 36 patients of diabetic retinopathy (DR) with CSME (Group–I) and another 35 patients of DR without CSME (Group – II) aged > 40 years were selected in Bangabandhu Sheikh Mujib Medical University (BSMMU) for this case control study from March’2013 to March’2014. Diagnosis of DR and CSME were carried out by history, clinical examination, fasting blood glucose (FBG), blood glucose 2 hours after breakfast, HbA1c (glycated hemoglobin), color fundus photograph (CFP) and optical coherence tomography (OCT) of macula as per ETDRS (Early treatment diabetic retinopathy study) criteria. Then fasting lipid profile was measured and compared between the groups. Result: Between two groups age, sex and occupation were matched. Dyslipidemia was present in 32 (88.9%) cases in Group–I and in 18 (51.4%) cases in Group – II, (p =0.001). Mean Total Cholesterol(TC) (211.8 mg/dl), Low Density Lipoprotein(LDL) (141.6 mg/dl) and Triglyceride(TG) (207 mg/dl) in Group – I were significantly higher than mean Total Cholesterol (183.3 mg/dl), Low Density Lipoprotein (118.5 mg/dl) and Triglyceride (143.5 mg/dl) in Group –II (p = < 0.05). But High Density Lipoprotein (HDL) was significantly lower in group- I (35.8 mg/dl) than group -II (41.1 mg/dl). Conclusion: Diabetic retinopathy with CSME has close association with dyslipidemia.