DOI: 10.36347/sasjs.2020.v06i04.009

Pages: 198-204

Introduction: Atherosclerotic coronary artery disease (CAD) is of great concern in young adults because of its potential to cause great incapacitation. This arena of cardiology has gained importance in South Asian countries, particularly Bangladesh due to increased prevalence that is related to traditional risk factors, altered life styles and inherent risk factors. Objective: To see the histopathological pattern of chronic arterial occlusive disease such atherosclerotic, thrombotic, vacuities. Materials and methods: The patients having surgery in Department of Vascular Surgery in BSMMU during from July 2017 to Jun 2018. A full clinical history along with routine and special investigations Histopathological examination report. This study will help to observed pattern of chronic arterial occlusive disease adult age group. The investigation’s and treatment facilities presently available in Bangabandhu Sheikh Mujib Medical University will be utilized. Additional facility in required for histopathlogical examination, which will be done from other reputed pathological laboratory also. A 1-year retrospective autopsy-based study was carried out in a BSMMU and patients aged<45 years with IHD were selected. Results: Out of 201 autopsied cases of IHD, 95 patients (17.4%) were young. Among these 95 patients, 84 (88.4%) had IHD related to atherosclerotic CAD; the youngest patient was 18 years old. Predictably there was sole involvement of left anterior descending artery and the presence of fibrous plaques. Irrespective of the plaque morphology, the commonest complication was thrombosis produced by plaque erosion seen in 36.9% of patients. Acute coronary insufficiency was noted in 52 patients (61.9%), while healed infarctions were surprisingly noted in 28 patients (33.3%). Screening for IHD in the young population may help to improve prognosis by detecting subclinical disease, although more studies are necessary to establish reference limits for this young population. .........