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Scholars Journal of Applied Medical Sciences | Volume-2 | Issue-02
Evaluation of Pulmonary Functions in Patients with Hypothyroidism Who Are on Conservative Management
Bhuvaneswari T, Kouser Banu K
Published: March 26, 2014 |
198
189
DOI: 10.36347/sjams.2014.v02i02.001
Pages: 495-497
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Abstract
Hypothyroidism is a state in which the thyroid gland does not produce enough amounts of the thyroid
hormones such as thyroxine (T4) and triiodothyronine (T3).Iodine deficiency is often cited as the most common cause of
hypothyroidism worldwide but it can be caused by many other factors. It can result the lack of activity of thyroid gland or
from iodine-131 treatment, and can also be associated with increased stress. Aim of the Study was to Determine the
Pulmonary Function Test parameters and Efficiency of lung Performances among the hypothyroidism Subjects. A total
number of 40 patients with clinical hypothyroidism (n=20) group I and (n=20) group II healthy subjects without pre and
past history of hypothyroidism served as a control group. Pulmonary functions test were evaluated by using simple
spirometer. Pulmonary Function Test parameters such as FVC, FVC%, FEV1, FEV1%, FEV1/FVC, FEF25-75, FEF25-
75%, were assessed. Biochemical parameters such as free triiodothyronine (FT3), free thyroxin (FT4) and thyroid
stimulating hormone (TSH) levels were measured in all subjects to know the hypothyroidism state among the subjects of
both the groups. From our study we concluded that the pulmonary function test parameters showed a lesser value in
hypothyroidism group I when compared to normal subjects group II. Spirometer evaluation of the respiratory function
revealed significantly lower values for FVC (L) P<0.05, FVC (%); P<0.05, FEV1 (L) P<0.05 and FEV1 (%) P<0.05.
Hypothyroidism affects the respiratory system, which in turn reduces the efficiency of respiratory system. Regular
monitoring of pulmonary function test among the subjects may rule out the possible outcomes among the hypothyroidism
subjects who are on regular therapy.