DOI: 10.36347/sasjs.2020.v06i05.005

Pages: 232-236

Introduction: Sjögren's syndrome (SS) is a relatively common autoimmune disease. It affects 0.2 to 3% of the population. For many years, the treatment of SS has remained mainly symptomatic, the doctors do not have drugs really capable of influencing the course of this disease, especially with regard to dry eye syndrome. The interest of this clinical case is to expose the complexity of the care of a patient presenting a severe dry eye syndrome and the therapeutic challenges that the ophthalmologist makes. Case presentation: M.T 65-year-old man, followed for 15 years in internal medicine for mixed connective tissue disease. The evolution was marked by the appearance of macular toxicity to A synthetic antimalarials, which required the discontinuation of treatment followed by a significant agravation of the dry eye syndrome and the ocular symptomatology. His care had involved a therapeutic adaptation and amniotic membrane graft and especially a fitting of a scleral lens. Conclusion: The treatment of dry eye is complex, difficult to conduct because of the multitude of mechanisms and the low reliability of the diagnostic criteria, as well as the frequent discordance between signs and symptoms. Treatment must first and foremost be based on a fine analysis of the mechanisms underlying dry eye and try to involve the patient in his treatment process.