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Scholars Journal of Applied Medical Sciences | Volume-2 | Issue-02
Isolation and Identification of Candida Species in Endoscopic Specimens of the Patients with Peptic Ulcer
Rajkumar Narasinghan, D. Senthil Pragash, Uma Maheswari Kuppusamy, Gnanasoory, Kalaiarasan
Published: March 28, 2014 |
242
163
DOI: 10.36347/sjams.2014.v02i02.019
Pages: 572-574
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Abstract
Gastrointestinal tract (GI tract) of humans has inner lining which is known as mucous membrane. These inner
lining of GI tract has major role in saving the stomach from acids present in the stomach. It prevents injury to the GI tract
by coating the walls. If the mucous layer of GI tract gets damaged then acid can damage the GI tract. The Candida is
yeast like fungi. The yeasts are spherical, oval or elongated and reproduce by budding. Candida albicans is normally
present in the mouth, intestine and vagina. Candida albicans is a frequent component of the human indigenous microbial
flora of the gastrointestinal (GI) tract of apparently healthy individuals. C. albicans can increase in numbers when this
balance is disturbed to cause candidiasis of the intestinal tract, or yeast infections of other parts of the body. C. albicans
causes thrush. The aim of the present study is to analyze the various fungi present in endoscopic specimens of acid
peptic disorder patients. Eighty samples were collected from the patients who are suffering from signs and symptoms of
peptic ulcer disorders. The samples were collected from both male and female patients with age varying from 21
years to 50 years. Samples were processed for fungal etiology. The direct smear Grams stain results showed a positivity
of 8.75 % for fungus. All the 7 fungi isolated belong to the Candida species. The present study concluded that along with
other bacterial isolates, Candida species are also present in the endoscopic specimens.