DOI: 10.36347/sjams.2014.v02i02.022

Pages: 584-588

The Objective of the study was to determine the morbidity and mortality in patients with a diagnosis of malaria with altered hematological and coagulation parameters. 100 patients of Malaria confirmed by PS.MPQBC or Antigen Assay underwent detailed clinical history, through physical examinations and investigated with haematological and coagulation parameters. This was followed by monitoring the outcome of patients with respect to morbidity and mortality. Of the 100 patients 14 patients had severe anemia (Hb % <6gm %) and all of these patients were falciparum, mixed infection and one case was Pl. Vivax infection. Thrombocytopenia was observed in 63% of the patients and severe thrombocytopenia (<50,000 cumn) was seen in 5% of the patients. PT and APTT was increased in 21% and 31% of the cases respectively. BT was increased in 5% of the cases. Increased BT is associated with high mortality. Severe anemia is a poor prognostic factor and adverse outcome. Thrombocytopenia, increased in PT, apt does not have any correlation to mortality. Mixed infection behaves like falciparum malaria.