DOI: 10.36347/sjds.2022.v09i07.004

Pages: 162-166

Introduction: Mucoepidermoid carcinoma (MEC) is a kind of salivary cancer with a wide range of biologic activity. Mucoepidermoid tumors are the only kind of cancer where histologic grading and clinical behavior features are linked. Given the relative rarity of this disease, while being the most prevalent of the salivary gland malignancies, this is a common problem in the MEC literature. The aim of the study was to observe the correlation of MEC histopathological grading and anatomical location. Methods: This observational descriptive cross-sectional multi-center study was conducted at the Department of Oral and Maxillofacial Surgery, Dhaka Dental College Hospital, Dhaka, Department of Otolaryngology &Head Neck Surgery, Dhaka Medical College Hospital, Dhaka, and Department of Otolaryngology-Head Neck Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh The study duration was 1.5 years, from July 2011 to December 2012. A total of 20 patients attending the study centers with diagnosed case of mucoepidermoid carcinoma of salivary glands was selected for the study following inclusion and exclusion criteria. Result: 40% of the participants were from the age group of 31-40 years, while another 30% were under the age of 21 years. 70% of the participants were female. Histological grading of the participants revealed 9 low grade, 8 intermediate grade, and 4 high-grade MEC tumor cases. High-grade tumor MEC had an association with increasing age and male gender. The swelling was a common clinical feature among all the participants, whereas ulceration was observed in 75% of high-grade tumor patients. Parotid gland was the most common location at 45%, followed by 30% tumors occurring at the palate. Among the 9 parotid gland carcinomas, 55.6% were from MEC intermediate grade, 33.3% from low grade and the remaining 11.1% from MEC high grade by histological grading. Among the 6 carcinomas of the palate, 50% were low grade, 33.3% were intermediate grade, ..........