DOI: 10.36347/sasjm.2022.v08i08.012

Pages: 572-579

Background: Peripheral spondyloarthropathy refers to spondyloarthropathy with predominant peripheral (arthritis, enthesitis or dactylitis) involvement which leads to significant disability. Objective: To assess the quality of life in patient with peripheral spondyloarthropathy (pSpA). Methodology: It was a cross sectional study conducted in the Department of Physical Medicine and Rehabilitation, BSMMU, Dhaka, from March 2021-February 2022. A total of 105 patients diagnosed with pSpA attending the study place were purposively selected for the study. Patients with concurrent systemic inflammatory rheumatic disease such as RA, SSc, lupus, Dermatomyositis were excluded from the study. Disease activity was measured by the validated Bengali version of The Ankylosing Spondylitis Disease Activity Score (ASDAS), including C-reactive protein (ASDAS-CRP) while health related quality of life was assessed by the validated Bengali version of Short Form Health Survey (SF) 12v2 instrument. Results: The mean age of the study participants was 38.8(±9.8) years where 68 (64.8%) were male. The mean duration of disease was 4.3(±3.3) years where 55 (52.4%) had up to 3 years’ duration of disease. The mean ASDAS-CRP was 3.9 ±0.8 where 69(65.7%) had very high Disease Activity Score. All (100.0%) study participants had arthritis and inflammatory back pain. HLAB27 was present in most of the study participants (N=101, 96.2%) and 99 (94.3%) had enthesitis. The mean Physical Component Summary (PCS) and Mental Component Summary (MCS) was 34.0(±7.8) and 41.3 (±7.7) respectively. There was weak negative correlation between age and PCS of SF-12 scores (r=-0.233, p=0.017). There was negative correlation between duration of the disease and PCS of SF-12 scores (r=-0.339, p<0.001) and MCS (r=-0.290, p=0.003). Again, there was moderate inverse correlation ASDAS-CRP and PCS of SF-12 scores (r=-0.406, p<0.001) and MCS of SF-12 scores (r=-0.461, p<0.001). Conclusion: Majority of the patients .........