DOI: 10.36347/sjams.2014.v02i03.016

Pages: 963-965

Nephrotic syndrome is a non-specific kidney disorder characterized by hypo proteinuria, hypo- albuminemia and edema. Edema is termed as excess amount of accumulation of fluid in the interstitial space. In nephrotic syndrome there is an increased risk of edema in the pleural cavity. This decreases the efficacy of pulmonary s in the patients. The aim of the study is to analysis the pulmonary function test parameters among specified nephrotic syndrome patients who are on stage 4 end stage renal failure. Totally 50 subjects were participated in our study among them 25 patients was evaluated with nephrotic syndrome. Among them 16 were male subjects and 9 were female subjects.The age group of whole 25 patients was 40 ± 13(Group I). 25 subjects were served as control group. Age group was between 42± 8 and both the genders were included in our study (Group II). FVC (% pred), FEV (% Pred), FEV / FVC, (% Pred), MVV (% Pred), PEFR (25-75% ). There was a decreased in Pulmonary functions parameters such as FVC, FEV1, FEV / FVC, MVV, PEFR in Nephrotic Syndrome patients(Group I) when compared with control group(Group II). Patients who are on end stage chronic renal failure stage IV with Nephrotic syndrome showed a decreased in pulmonary function test parameters. The reason behind this is due to ascites and edema throughout the body. Ascites inflates the diaphragm to move upward which reduces the respiratory endurance among patients.