DOI: 10.36347/sjams.2014.v02i02.078

Pages: 862-864

The purpose of this study was to know prevalence and susceptibility pattern of extended spectrum β- lactamases(ESBLs) at our tertiary care centre. A total of 660 non-repetitive clinical isolates of Enterobacteriaceae obtained from various clinical samples of which isolates that exhibited intermediate/ resistance to third generation cephalosporins were screened to detect ESBL producers by double disk synergy test. ESBLs were confirmed by phenotypic confirmatory test and E-test ESBL strips. Among 660 Enterobacteriaceae isolates, 125(18.9%) of which were ESBL producers. E.coli 53.6% was the largest group followed by K. pneumoniae 32.8% and all other species together comprised 13.6%. Continued monitoring of drug resistance is necessary in clinical settings for proper disease management.