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Scholars Journal of Applied Medical Sciences | Volume-10 | Issue-09
Bacteriological Profile of Clinical Isolates from Urinary Samples and Prevalence of CAUTI at a Tertiary Care Hospital
Dr. Samina Kausar Tabassum, Syed Imran Ahmed, Dr. Mirza Atif Baig
Published: Sept. 10, 2022 | 129 130
DOI: 10.36347/sjams.2022.v10i09.012
Pages: 1492-1499
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Abstract
Background: Urinary tract infections (UTIs) attributed to the use of an indwelling catheter is one of the most common infections acquired by patients in health care facilities. This infection is associated with varied microbiological etiology. Catheter-associated urinary tract infection (CAUTI) is an important cause of morbidity and mortality in India. The objective of this study was to find the prevalence of CAUTI infection and to determine their antibiotic profile. Aims and Objectives: The aim of the study was to provide a baseline information in the context of culture positivity rate of urinary isolates and prevalence of catheter associated urinary tract infections (CAUTI), to identify the associated microbial, and to determine their susceptibility pattern to commonly used antimicrobial agents for prophylactic and empiric therapy. Materials and Methods: This prospective study was done on nonrepetitive urine samples from all age group patients of both inpatient and outpatient department. Semi quantitative bacterial culture was performed, and isolates were identified and antimicrobial sensitivity tests were carried out by Vitek-2 compact automated method. Results: Significant bacteriuria was observed among 257/1543 (16.65%) urine samples. Among bacterial isolates, Gram negative bacilli predominate. Escherichia coli 7/17 (44%) being the most common isolate followed by Klebsiella (35%). The incidence of CAUTI/1000 catheter days observed in our study was 2.77. Total 3 CAUTI were identified from July 2021 to June 2022, out of which 2 were Klebsiella pneumoniae and 1 isolate was Enterococcus faecium. Conclusions: Uropathogens from CAUTI patients exhibit significantly higher resistance to most antibiotics than non- CAUTI isolates. This is an important factor to take into consideration when choosing correct treatment options for patients with urinary tract infection. Klebsiella pneumoniae is one of the important notable pathogens causing nosocomial infections.............