DOI: 10.36347/sjmcr.2020.v08i01.018

Pages: 56-59

Introduction: Consumption coagulopathy or disseminated intravascular coagulation (DIC) corresponds to uncontrolled activation of coagulation in an anatomically intact vascular network leading to fibrin deposition in the vasculature, organ dysfunction, and consumption of clotting factors and platelets, and life-threatening hemorrhage. This is an acute and severe pathological situation with a very unpleasant prognosis providing very high mortality. Materials and methods: The study was conducted on a complicated case of chronic myeloid leukemia (CML) with disseminated intravascular coagulation (DIC). Observation: We report a case of a 75-year-old patient followed for type II diabetes and dyslipidemia under treatment who presented with generalized fatigue and a history of left hypochondrium discomfort. The abdominal examination revealed a splenomegaly (5 cm from the cost overhang). The rest of the clinical examination was without peculiarity. On investigation, he was found to have a major hyperleukocytosis at 111.5 G / l with a leukocyte count as follows: PNN at 95.89 G / l, PNE at 1.115 G / l, PNB at 0 G / l, Lymphocytes at 11, 15 G / l and monocytes at 3.345 G / l. The hemoglobin level was 8.3 g / dl with a VGM at 86 µ3, a TCMH at 29pg and a CCMH at 32.3 g / dl. The reticulocyte count was around 28,960 element / mm3. The platelet count was 279 G / L. The blood smear objectified the presence of a 43% myelemia made up of 20% of myelocytes and 23% of metamyelocytes with a rate of circulating blasts of 9%. A myelogram was performed one day after had objectified a very rich marrow with the presence of many megakaryocytes and major hyperplasia of the granular line at 86% is subject to compliance with the maturation pyramid without significant hiatus.