DOI: 10.36347/sjmcr.2020.v08i01.029

Pages: 96-99

Introduction: Eosinophilic pancreatitis is a rare cause of pancreatitis. It is characterized by localized or diffuse infiltration of the pancreatic gland by eosinophilic polymorphonuclear cells. It poses the problem of differential diagnosis with a pancreatic tumor, hence the interest of histological evidence by invasive means. Case report: We present a case of eosinophilic pancreatitis in a 37-year-old man who was diagnosed after an endoscopic biopsy in front of an obstructive mass of the head of the pancreas simulating a pancreatic tumor. In contrast to the data in the literature, our patient had only eosinophilic infiltration of the pancreas with no history of symptoms related to hypereosinophilia or to a high level of immunoglobulins E. The second peculiarity in our patient is the concomitant revelation of ulcerative colitis. Conclusion: Eosinophilic pancreatitis is a rare and often misdiagnosed clinical situation. Correct and precise diagnosis avoids unnecessary interventions. Echo-endoscopy with sample for histological study presents a fundamental means for the diagnosis of eosinophilic pancreatitis.