DOI: 10.36347/sjmcr.2022.v10i09.012

Pages: 907-910

Pyoderma gangrenosum (PG) is a rare entity belonging to the neutrophilic dermatoses. It is an inflammatory dermatosis with a chronic evolution by relapses, often revealing an associated underlying disease. The location to the breast represents is unusual, poorly documented in the literature localization and whose diagnosis remains difficult to establish. We report the case of a 51-year-old female patient, with no particular pathological history, who presented for 4 months a painful ulceration of the left breast, of centrifugal extension measuring 9 cm of the great axis, with a hemorrhagic base, well limited by an inflammatory violaceous border with no other localizations and no notion of trauma. A skin biopsy revealed a dermal neutropilic infiltrate. The patient was given oral corticosteroid therapy at a dose of 0.5mg/Kg/day coupled with topical corticosteroids. The results were satisfying: the ulcer gradually healed and the pain reduced. Pyoderma gangrenosum is a poorly understood clinical entity, classically presenting with inflammatory and painful skin ulcerations. It may occur in a post-surgical or post-traumatic context defining the phenomenon of pathergy described in neutrophilic dermatoses. Treatment is mainly based on topical corticosteroids or in severe cases oral immunosuppressants and the treatment of the underlying pathology.