DOI: 10.36347/sjams.2022.v10i09.020

Pages: 1542-1546

Introduction: Thyroid hormones are crucial for renal development and physiology. Thyroidal hormones affect the cardiovascular system through their influence on renal blood flow as it modulates the glomerular function, the tubular secretory and absorptive capacities as well as the electrolyte pumps and the kidney structure. Objective: To assess the thyroid function abnormalities in patients with different stages of chronic kidney disease. Materials and Methods: The cross sectional observation study was conducted in Department of Medicine, 250 Bed District Hospital, Habiganj, Bangladesh from January to April 2021. Included 54 CKD patients not on dialysis, who are only on conservative management. Results: In our study the age matched graph shows that maximum number of patients in the category of 40-49 years with 8 males and 6 females, 50- 59 years had 8 males and 6 females, whereas between 60 to 69 years there were 6 males and 6 females. The extreme age groups had few patients chronic kidney disease above 70 there were 2 females and 2 males between 18-29 years there were 3 males and 3 females and 30-39 years had 1 male and 3 females. In our study the number of chronic kidney patients having low T3 were 39 which constitutes 72.2%,the patients with normal T3 were 12 constituting 22.2% and those with high T3 were 3, suggesting primary hyperthyroidism, so excluding them 75% of our patients had low T3 syndrome. In our study 39 patients had low T3, 26 had low T4 with 49 patients being normal TSH, only 4 had high high TSH. Excluding patients with primary hypothyroidism. Patients with low T3 low T4 were clustered in more towards end stage renal disease with 60%. Patients also were in moderate number with low T3 and low T4 in stage 4 chronic kidney disease. 20% in stage 3 chronic kidney disease T4 and TSH were almost normal with only 10% patients had low T3 syndrome. In stage 2 chronic kidney disease 10% had low T3, low T4 with rest being normal TSH. In our study patients .....