DOI: 10.36347/sjams.2017.v05i03.006

Pages: 711-716

Total hip arthroplasty (THA) is one of the most frequent interventions in orthopedics. This is a surgical procedure at high risk of bleeding. Tranexamic acid (ATX), a synthetic antifibrinolytic, is an option of choice in the blood economy. It is therefore felt necessary to initiate the study on the interest of the ATX in the prevention of bleeding during the implantation of primary THA. A retrospective study subjects exposed and unexposed single-center, comparative between January 1, 2013 and March 31, 2014. All patients who had undergone primary total hip arthroplasty were enrolled and divided into 2 groups of 30:- Group ATX + patients received the administration of tranexamic acid in perioperative - Group ATX - patients didn’t receive tranexamic acid as the control group. Sixty patients had received primary THA, divided into two groups of 30. The mean age of patients was comparable in both groups. The sex ratio was 1.1 with no significant gap between the two groups (p = 0.2). The average BMI was 23.60 ± 3.5 kg / m² in ATX + Group and 24.2 ± 3.5 kg / m² in ATX – group (P = 0.6). The average hemoglobin was 12.9 ± 1.1 g / dL in all patients. The surgical indications were identical in the two groups. Both anesthetic methods were practiced, spinal anesthesia and general anesthesia with no significant difference in both groups (P = 0.9). The mini-invasive incision was made more than 70% in both groups (P = 0.9).