DOI: 10.36347/sjams.2017.v05i03.021

Pages: 796-799

The objective is to study the efficacy, safety and acceptability of ormeloxifene in the medical management of AUB. This is a Hospital based interventional study which included a sample size of 52 Samples. 52 cases of AUB were recruited. Each was given 60 mg of ormeloxifene twice weekly for 3 months and then once a week for next month. Follow up was done at 1,3 and 4 month. Primary outcome measures were menstrual blood loss, haemoglobin concentration and endometrial thickness. Secondary outcome measures were the acceptability and side effects of ormeloxifene. The mean pretreatment HB concentration was significantly increased and means pretreatment endometrial thickness was reduced. Thus ormeloxifene is safe and effective drug for medical management of AUB. It is nonsteroidal, pharmacologically and metabolically safe oncologically protective and cost effective too.