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Scholars Journal of Applied Medical Sciences | Volume-5 | Issue-03
Determination of required insulin dose to control blood sugar in patients with Gestational diabetes mellitus
Seyed Bahman Ghaderian, Masoud Haghighizadeh, Sholeh Saeb
Published: March 28, 2017 | 113 73
DOI: 10.36347/sjams.2017.v05i03.023
Pages: 805-815
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Abstract
Nowadays rate of gestational diabetes mellitus (GDM) is increasing and it has numerous complications for both mother and newborn, so appropriate and timely treatment of GDM is very important. Insulin is the most common treatment to control blood sugar in GDM. Knowing the amount of insulin required during pregnancy could help doctors to better control blood sugar in women with GDM. This study aimed to determine the amount of insulin required to control blood sugar in patients with gestational diabetes. This is a retrospective study, carried out using medical records of 225 pregnant women aged 18 to 45 years diagnosed with GDM for the first time referred to Imam Khomeini Teaching Hospital in Ahvaz during 2016. Total daily insulin dose (TID) during pregnancy was recorded as units per kilogram, and the amount of insulin required in women with GDM was evaluated based on the characteristics of mother. The collected data were analyzed using SPSS version 23.00 (SPSS Inc., Chicago, IL, USA). This study showed that the amount of insulin required to control blood sugar by increasing gestational age significantly increases. So that the required insulin in gestational age less than 12 weeks: 0.52±0.09 units / kg / day, in 13 to 26 weeks: 0.64±0.05 units / kg / day, in 27 to 35 weeks: 0.73±0.08 units / kg / day, and more than 36 weeks to birth: 0.85±0.03 units / kg / day (P < 0.05).