DOI: 10.36347/sjams.2017.v05i03.036

Pages: 881-885

Multidrug resistance tuberculosis (MDR-TB) is one of the infections among the human immunodeficiency virus (HIV) seropositive cases. Varied clinical and radiological manifestations and treatment outcomes are being observed according to the immune status of the HIV serpositive MDR-TB patients. In this retrospective study, the data of the diagnosed cases of MDR-TB patients with HIV seropositivity who were registered in DR TB centre of Southern Odisha, over a period of three years. The detailed basal demographic characteristics, clinical, radiological, laboratory investigation findings, the treatment outcomes were noted and analysed statistically. In this setup, Maximum patients were (61.54%) within the age range of 26-35yrs with male preponderance. (M: F = 12:1). 88.89% of them were from rural areas and all were Hindus. The major clinical presentations were anaemia (100%), fever (84.61%), persistent cough (92.31%) weight loss (46.15%), and decreased appetite (38.46%). The radiological findings were cavitary lesions (53.84%) and infiltrations (46.15%) Among this study sample, only 23.08% of patients were declared to be cured, 46.15% died following successful treatment. 23.08% patients were declared to be default and 7.69% were lost to follow up within the study period. In the present study, MDR –TB patients co-infected with HIV were commonly observed among adult males. The treatment outcomes were poor probably due to non-adherence to multiple drug regimens under RNTCP and ANTI-HIV drugs.