DOI: 10.36347/sjams.2017.v05i03.066

Pages: 1065-1069

Dexmedetomidine is a α2 -adrenoreceptor agonist with sedative, analgesic and anxiolytic properties it is known to be used as General Anesthetic adjuvant. It has useful action like minimal respiratory depression with Cardio protection, Neuroprotection and Renoprotection with added advantages like anesthetic and analgesic sparing actions. In the present we tried to evaluate the effect of dexmedetomidine as anesthetic adjuvant on variables and postoperative pain scores and need for rescue analgesics and anti-emetics and resumption of bowel function. The study was performed in CAIMS Karimnagar. 60 patients divided into three groups of 20 each were randomly selected and allotted. The patients were undergoing various abdominal surgical procedures like Laparoscopic Cholecystectomy, Hysterectomy and Appendectomy. The first group (Group I) was the control group they received IV saline 10ml, the second group (Group II) was the [Dex 0.5] group they received Dexmedetomidine 0.5 µg/Kg/hr IV and third group (Group III) [Dex 1.0] received Dexmedetomidine 1 µg/Kg/hr IV. Anesthesia was maintained with N2O to O2 mixture of 60:40. MAP values were maintained within 25% of the baseline values. Recovery times from tracheal extubation, modified Alderete score, VAS scores, tolerating liquids, and passage of flatus were noted. Mean duration of surgery was 156 ± 25, 140 ± 30 and 126 ± 45 in group I, Group II and Group III respectively.