DOI: 10.36347/sjams.2017.v05i03.082

Pages: 1147-1150

Androgenetic alopecia is condition of patterned hair loss. It is a psychologically distressing condition. Mesotherapy is a technique of delivery of topical solutions in the middle layer of the skin. The aim is to evaluate the efficacy and safety of mesotherapy using finasteride versus oral finasteride for the treatment of androgenetic alopecia in forty male patients. We selected forty patients of androgenetic alopecia for the study. The patients were divided into two groups of 20 patients each. In group I patients, mesotherapy was given using topical finasteride solution with a mesotherapy needle using nappage technique. In group II patients, oral finasteride 1 mgm was given. After six sessions, excellent improvement was seen in 15(70%) patients in group I and 12(60%) patients in group II, very good improvement was seen in 3(15%) patients in group I and 2 (10%) patients in group II, good improvement was seen in 1(5%) patients in group I and 5 (25%) patients in group II, average improvement was seen in 1(5%) patients in group I and 3 (15%) patients in group II and no improvement was seen in 5(25%) patients in group I and 10 (50%) patients in group II. But, the difference of improvement between the two groups was no statistically significant. The commonest side effect (Table IV), was loss of libido seen in 2(5%) patients in mesotherapy group and 4 (10%) in oral finasteride group, folliculitis was seen in 2(5%) patients in mesotherapy group and in none of the patients in the oral finasteride group and erectile dysfunction was seen in none of the patients in the mesotherapy group and in 2(5%) patients on oral finasteride group. Loss of libido in the mesotherapy group indicates systemic absorption of the drug. Mesotherapy using topical finasteride is a good option for the treatment of patterned hair loss in men.