DOI: 10.36347/sjams.2017.v05i01.035

Pages: 169-174

Tuberculosis remains one of the prominent causes of death in HIV/AIDS patients. A few studies have been found in the literature to discuss the risk factor for death and outcome of the treatment with Anti-Tuberculosis Treatment (ATT). The aim of this study is to identify predictors of mortality in TB-HIV co-infected patients. It was an observational perspective study which included 100 patients with TB-HIV co-infection on ATT and HAART. Patients were followed up at 6 and 12 months and after complete history, GPE was done and basic laboratory investigations were also repeated. Functional status was assessed according to the mobility of the patients at each step. The statistical analysis was done with the help of Pearson chi square test and T test. The study was conducted on 100 patients. Mortality rate in TB/HIV co-infected patients were high (i.e. 15% and19% at 6 months and 12 months). The CD4 count at presentation was 500 cells/mm3 in majority (90%) of the cases. The CD4 count of died patients were below 150cells/mm 3. Most of the subjects who died had Hb at the presentation time less than 9 g/dL. Malnourished cases were at high risk of death who has BMI less than 18.5. Bedridden cases were at high risk of mortality. Percentage of EPBT was greater than PBT (60% and 40% respectively). Bed ridden cases had poor outcome. With treatment the patients improved in terms of Hb, BMI, CD4 count and functional status of the patients.